Intake of water, potassium, and phosphate affect change of body weight, serum potassium and phosphate level, all of them values associated with the survival of dialysis patients. We developed SMART-D to support patients’ self-management in order to improve long-term survival of those patients. Patients can check their lab data—serum potassium and phosphate level—and change of body weight by using the system; if the values meet the level suggested by the guidelines, patients will be more motivated to adhere to healthy behavior; alternatively, if the values do not meet the suggested level, patients should try to modify their behavior in order to achieve the treatment goals. A two-week pilot study of 20 dialysis patients was conducted, showing that quality of life tended to improve for the patients who used SMART-D, compared with that for the control patients. We plan to do a longer study with a larger number of patients.